UNSW Embryology

WEEK 1 Development- in vitro fertilization

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1949 8 cell mouse embryo -> blastocyst (in saline and egg yolk)

1956 8 cell mouse embryo -> blastocyst (first embryo culture medium)

1957 2 cell mouse embryo -> blastocyst

1958 8 cell mouse embryo -> blastocyst, then transferred to pregnant recipient

1960's development of culture requirements for mouse mebryos

1965 2 cell mouse embryo -> blastocyst, then transferred into pseudopregnant recipient

1968 zygotes from mouse -> blastocysts

1968,70 2 & 4 cell rabbit embryos -> blastocyst in serum supplemented medium

1970,71 1 & 2 cell rabbit embryos -> blastocyst in defined medium

1970,81 Culture of in vitro fertilized human embryo -> 16 cells -> blastula

1998 Cloning of adult sheep "dolly"

Modified from Bavister, B.D., Human Reproduction Update, 1:91-148 (1995)

Lecture notes from the Anat 3311 1997 Science Embryology course compiled and written by Dr Mark Hill. Some notes derived from historic class notes.
Note Links to OMIM Entries are copies of originals for computers without internet access. Computers with internet access can directly access the database.

m.hill@unsw.edu.au
Date Last Modified: 19/3/99
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