Cushing disease
Chapter: 21
Overproduction of adrenal cortical glucocorticoids secondary to overstimulation by ACTH. The latter may be due to an ACTH producing basophilic adenoma or adenomas of the pituitary gland, hyperplasia of same, or increased release of Corticotroph Release Factor (CRF) from hypothalamic neurons, reaching the pituitary through the portal venous system.
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