Granulation tissue, base of duodenal ulcer, H/E x 100
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This photomicrograph shows the essence of granulation tissue: young, plump fibroblasts; collagen; chronic inflammatory cells; and angiogenesis, typified by young capillaries with swollen endothelial cells. If the chronic irritation is erradicated by treatment of the ulcer, the granulation tissue will slowly organize to form a mature scar, and the intestinal epithelium will regenerate over the top of it.