angiogenesis
Chapter: 3
During the formation of granulation tissue, the process of angiogenesis leads to the formation of numerous small capillaries. These capillaries can be seen from the surface of the wound, and resemble small red granules, which accounts for the name. The exuberant growth of new blood vessels is brought about by the influence of fibroblast growth factor (FGF), and perhaps other cytokines. Angiogenesis also occurs during the formation of tumors, both benign and malignant. Certain infections also induce angiogenesis (e.g., Bartonellosis and bacillary angiomatosis).
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