Sezary syndrome, peripheral blood
Click picture to enlarge. Close window to return

This patient had a history of Mycosis fungoides. He presented with generalized erythroderma and was found to have a WBC count of 26,000/ul. The slide shows the appearance of the atypical lymphocytes, which display nuclear folding and convolutions, typical of Sezary cells. The cells had a T-cell phenotype when analyzed by flow cytometry. Sezary Syndrome is the leukemic phase of Mycosis fungoides.