UNSW Embryology

Human Menstral Cycle Smears

Secretory


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Menstrual Cycle

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Smears

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Day 23-28

Late Secretory, premenstrual

stratum spinosum cells (blue) mainly with a few stratum corneum cells (red). Clustering of cells occurs at this stage and both leukocytes and bacteria are prevelant.

Human Vaginal Smears

Stratum corneum (eosinophilic, red) and stratum spinosum (basophilic, blue) cells throughout the menstrual cycle.

Observe cell size, proportion of pyknotic nuclei, stain intensity and cell morphology. Leukocyte number is variable, but not a reliable criteria.