UNSW Embryology

Gastrointestinal Tract Development
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DEVELOPMENTAL ABNORMALITIES

I. INTESTINAL MALROTATION

What abnormal embryological processes could interfere with normal rotation and fixation of the gut?

 OMIM Database Entry- Volvulus of Midgut (about this entry)

II. SITUS INVERSUS VISCERA

Disturbance of the lateralisation of the liver may produce transposition of some or all of the foregut and its derivatives.

1. Stomach

2. Pancreas

3. Duodenum - jejunum

4. Spleen

5. Bile

Also in situs inversus the anatomical relations of the duodenum, pancreas, bile ducts and portal veins may be reversed or disordered.

OMIM Database Entry- Situs Invertus (about this entry)

III. MECKEL'S DIVERTICULUM

OMIM Database Entry- Meckel's Diverticulum (about this entry)

IV. HIRSCHSPRUNG'S DISEASE (INTESTINAL AGANGLIONOSIS)

OMIM Database Entry- Hirschsprung's Disease (about this entry)

OMIM Database Entry- Hirschsprung's Disease 2 (about this entry)

V. GASTROINTESTINAL ABNORMALITIES, MULTIPLE

OMIM Database Entry- Multiple GIT Abnormalities (about this entry)

OMIM Database Online Mendelian Inheritence in Man Database. OMIM

Internet Search this database with the keyword "" or the above abnormality names.

Note: This database is an external link, not accessible from some computers in the School of Anatomy.
A List of the entries found, searching for "Hirschsprung" is available for these computers.

Enter one or more search keywords:

To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. See Query Help for other ways to search.
Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors:
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Self Assessment Questions

  1. What is a pharyngeal arch and pouch? List the muscle, arch cartilage and nerves of each arch. List the derivatives of each pharyngeal pouch.
  2. Describe the main steps in the development of the tongue.
  3. How is the thyroid gland developed?
  4. What are the derivatives of the fore-, mid- and hind-gut?
  5. What is the buccopharyngeal membrane?
  6. Describe the normal development of the face and palate. List the major malformations of this region and their possible causes.
  7. How is the liver developed?
  8. What are the main processes involved in the elongation and rotation of the stomach and intestinal region?
  9. Describe the development of the pancreas.
  10. How does the myenteric plexus develop?
  11. List the basic principles in the development of the peritoneum.
  12. What are the functions of the liver and pancreas in the fetus? Does the gastro-intestinal tract function in the fetus?
  13. What are the consequences of malrotation of the gut?

PubMed Database

Online Medline Database PubMed- Medline

National Library of Medicine (US) search service to access the 9 million citations in MEDLINE and Pre-MEDLINE (with links to participating on-line journals), and other related databases.

Internet Search this database or use the form below with the keyword or related topics. You can also restrict to reviews or by date published.

  • Note: This database is an external link, not accessible from some computers in the School of Anatomy.
  • A Selected List of References from March 1999 search results for " and " is available for these computers.

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PubMed

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About Notes

  • These lecture notes from the Embryology course compiled and written by Dr Mark Hill.
  • Note Links to PubMed Medline Entries are copies of originals for computers without internet access. Computers with internet access can directly access the database.
  • Note that reference lists are only relevant to the date that the original search was carried out.

Links
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m.hill@unsw.edu.au
Date Last Modified: 30/3/99
This site maintained by Dr M. Hill