THE MALE REPRODUCTIVE SYSTEM: II
ALBERT S. BERKOWITZ, PH.D.
HISTOLOGY FALL 1994 - Male Reproductive System Laboratory: II
Slide #117 Testis and epididymis, monkey
This section shows the monkey testis which by now you should all be able to identify and the
epididymis. The epididymis is well fixed and you should be able to see the tall
pseudostratified columnar epithelial cells with the stereocilia. Note the layers of smooth
muscle which surround the epithelium. Review functions of epididymis.
Slide #19 Epididymis, human
Again this tissue is not particularly well fixed. However, you should still be able to identify
the pseudostratified columnar epithelium. Note the stereocilia on the luminal free epithelial
surface. The epithelium rests on a very delicate basement membrane which is difficult to
identify on this slide. A very prominent Golgi comlex can be seen just above the nuclei of the
epithelial cells. The epithelium is surrounded by a layer of smooth muscle which becomes two
layers in the tail. What purpose do you think this layer of smooth muscle might serve? Note
the spermatozoa in the lumen of the epididymis. Note: Some of your slides may also have
vas deferens.
Slide #21 vas deferens and epididymis, immature monkey
Once again note that the epididymis is lined with a tall pseudostratified columnar epithelium
with stereocilia. Using your imagination and your high power objective you should be able to
see the large supranuclear Golgi complex. Note the layer of smooth muscle (two layers if the
section is from tail) beneath the basement membrane. Note that both the outer tubular profile
and the inner, luminal contours are smooth. Locate and identify the vas deferens and its three
layers of smooth muscle. The vas deferens is lined with tall columnar cells with stereocilia.
The outer tubular profile is smooth but the inner luminal contour demonstrates folds.
Slide #114 vas deferens, human
Identify: Ampullary region of vas deferens with deeply folded lumen.
Slide #16 Spermatic cord, human
Identify the vas deferens. Review its epithelium and structure. Identify nerves and vessels.
Note the pampiniform plexus of veins. What is its function? Do you see skeletal muscle
within the spermatic cord? What is this muscle and its function?
Slide #15 and 18 Seminal vesicle, human
Identify:
- irregular pouchlike folds of mucosa
- bridges formed from folds
- lipofuscin pigment in epithelial cells
- inner circular and outer longitudinal smooth muscle layers
Slide #20 Prostate, human
This tissue is very poorly fixed but you should still be able to appreciate the glandular nature
of the prostate, which in reality is a conglomerate of compound, tubuloalveolar glands. The
epithelium is simple cuboidal/columnar or pseudostratified columnar but is difficult to
appreciate in this slide. The form of the glands is irregular but there are usually folds of
epithelium (with this connective tissue core) which project into the luminae of the glands.
Unlike the seminal vesicle, the folds do not form bridges. Note the muscle fibers which
penetrate between the prostatic lobules.
Slide #18 Penis, human
In this slide, the penile skin has been stripped away. However, you should be able to see the
paired dorsal columns, the corpora cavernosa and the single ventral column, the corpus
spongiosum, which contains the urethra. Unfortunately, the urethral epithelium is poorly
preserved. In the columns note the extensive system of trabeculae (fibroelastic tissue
containing smooth muscle) and an equally extensive system of blood sinusoids, the venous
sinuses. Note that a very dense connective tissue layer surrounds the corpora cavernosae and
to a lesser degree, the corpus spongiosum. This layer is the tunica albuginea of the penis.
Proximally, the tunica albuginea completely separates both corpora cavernosae; distally, this
septum is incomplete. You may be able to locate the dorsal vein lying in the loose connective
tissue external to the corpora cavernosa.