Yolk sac tumor

Chapter: 17
A malignant germ cell tumor of the testis, typically found in children under the age of fIve years. Histologically the tumors appear variegated and show numerous patterns of cell growth, labeled as reticulated, microcystic, papillary myxoid, etc. Schiller-Duval bodies resembling fetal glomeruli are often present. The tumor cells secrete AFP. Surgery is curative. Similar yolk sac tumor elements may be found in teratocarcinomas, accounting for the elevated AFP in the blood of patients harboring these tumors.