Schlicter testing
Chapter: 9b
The lowest dilution of serum that kills 99.9% of the inoculum. Blood is drawn during the peak and trough of the antimicrobial being utilized, then the serum is diluted in broth and tested against the microbial isolate. This test is usually done only in tertiary centers, by infectious disease specialists, to treat difficult cases of endocarditis, osteomyelitis, or sepsis in an immunocompromised patient.