Lupus erythematosus

Chapter: 24
This may occur as a disease of the skin alone, discoid lupus, or as part of systemic lupus erythematosus; the pathology is the same in both. The patients are photosensitive, the erythematous rash typically occurs on sun exposed skin. Lymphocytes migrate into the epidermis and there is vacuolar degeneration of the basal cells and epidermal atrophy.