Leukemia
Chapter: 20b
Malignant proliferation of hematopoietic cells, characterized by replacement of bone marrow by neoplastic cells. The leukemic cells usually are present in peripheral blood, and may infiltrate other organs of the reticuloendothelial system, such as liver, spleen and lymph nodes. Leukemia is broadly classified into acute and chronic leukemia, with multiple distinct clinicopathologic entities subclassified in each category.
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