Integrins
Chapter: 2
This class of adhesion molecules (see separately) is key to cell-cell and cell-matrix interactions that are important in genesis of the cellular phase of the inflammatory response. They are particularly important as the molecules that increase adherence of leukocytes to the surfaces of endothelial cells, thereby allowing the leukocytes to crawl to the gaps between endothelial cells and transmigrate to the extravascular space.
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