Immunoblastic lymphoma
Chapter: 20b
Immunoblastic lymphoma is a high grade, aggressive non-Hodgkin lymphoma. The neoplastic cells morphologically resemble a benign immunoblast, and have a large centrally placed nucleolus. Immunoblastic lymphoma frequently occurs in the setting of patients who have disordered immune states and in the HIV-positive population. In most treatment protocols, this type of lymphoma is grouped with diffuse large cell lymphoma.