Hypoparathyroidism
Chapter: 21
Decreased PTH secretion due to parathyroid absence or agenesis Hypocalcemia results from an inadequate release of Ca2+ from the bone. Aside from the accidental removal of the parathyroid during thyroidectomy, the most common cause of hypoparathyroidism is the developmental absence of the parathyroids. Because the parathyroids and thymus arise from the same embryonic anlagen, a condition known as DiGeorge syndrome, exhibiting not only hypoparathyroidism but also T-cell immunodeficiency, results from a failure of development both thymus and parathyroids.