Fibrin
Chapter: 2
Fibrin is the product of an activated coagulation system. It forms in the extravascular space by cleavage of fibrinogen. It is an important component of a blood clot, as well as a thrombus. However, in the context of this section, it is important to understand that fibrin can be a prominent part of exudates that develop when vascular permeability/injury has been sufficiently great to allow a large molecule like fibrinogen to cross into the extravascular space. Fibrinogen is cleaved in the extravascular space to form fibrin.