extracellular matrix
Chapter: 3
A stable complex of macromolecules that surrounds cells. It can be thought of as a framework for cell migration during the embryologic development of the organism. In many ways, the extracellular matrix seems to actually direct cell migration, and/or facilitate cell-to-cell communication. The matrix consists of 5 primary components: 1) basement membrane; 2) elastic fibers; 3) structural glycoproteins such as fibronectin; 4) proteoglycans; and 5) collagen. Fibroblasts actively secrete components of the matrix. Fibronectin and hyaluronic acid are some of the first glycoproteins deposited in a wound.
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