Erythroblastosis fetalis (hemolytic disease of the newborn):
Chapter: 20a
Hemolytic disease in the fetus or neonate due to maternal antibodies against fetal RBC's. Hemolytic disease may occur when the maternal antibody is against a fetal antigen of the RH or ABO blood group system. Alloimmunization of RH negative mother by fetal Rh positive cells may occur at delivery, and therefore, it is future pregnancies which are at risk of developing hemolytic disease. The use of RhoGam has greatly reduced the incidence of RH hemolytic disease.
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