Definition for:Acute Interstitial Pneumonia (AIP):

Acute Interstitial Pneumonia (AIP):

Chapter: 12
(Synonymous with Hamman-Rich Syndrome) is a rapidly progressive acute interstitital pneumonitis that histologically resembles the organizing stage of Diffuse Alveolar Damage (DAD); some individuals view this as a variant of DAD. AIP most frequently affects young adults, who present with a flu-like syndrome, and bilateral lung infiltrates. These patients rapidly develop respiratory failure requiring mechanical ventilation. The prognosis is grave with a majority of patients dying within two months of onset.