TABLE 13a. Drugs Used in the Prophylaxis of Malaria

Drug                                  Adult dose                 Pediatric dose
---------------------------------------------------------------------------------------
Mefloquine                    228 mg base (250 mg salt)   15-19 kg: 1/4 tab/wk
(Lariam(R))                   orally, once/week           20-30 kg: 1/2 tab/wk
                                                          31-45 kg: 3/4 tab/wk
                                                          >45 kg: 1 tab/wk

Doxycycline                   100 mg orally, once/day     >8 years of age:
                                                          2 mg/kg of body weight
                                                          orally/day up to adult dose
                                                          of 100 mg/day

Chloroquine phosphate         300 mg base (500 mg salt)   5 mg/kg base (8.3 mg/kg salt)
(Aralen(R))                   orally, once/week           orally, once/week, up to
                                                          maximum adult dose of
                                                          300 mg base

Hydroxychloroquine sulfate    310 mg base (400 mg salt)   5 mg/kg base (6.5 mg/kg salt)
(Plaquenil(R))                orally, once/week           orally, once/week, up to
                                                          maximum adult dose

Proguanil                     200 mg orally, once/day     <2 years: 50 mg/day
                              in combination with         2-6 years: 100 mg/day
                              weekly chloroquine          7-10 years: 150 mg/day
                                                          >10 years: 200 mg/day

Primaquine                    15 mg base (26.3 mg salt)   0.3 mg/kg base (0.5 mg/kg
                              orally, once/day for 14     salt) orally once/day for
                              days                        14 days