Classify tumors on the basis of their clinical behavior and histopathologic features.
List the common forms of carcinoma and sarcoma and describe their benign equivalents, and tissue of their origin.
Discuss metastasis with respect to patterns of spread and biology of invasion.
Explain the principles of tumor grading and staging, and the TNM system.
Discuss chemical, physical, and viral carcinogens that could affect humans.
Discuss the multi-stage nature of chemical carcinogenesis, and relate it to the development of cancer in humans.
Describe the evidence for viral carcinogenesis in humans, with special emphasis on human papilloma virus, Epstein-Barr virus and hepatitis B virus.
Discuss the role of oncogenes and tumor suppressor genes in human tumor development.
Describe the host's immune response to neoplasia.
Describe the significance and the clinical value of tumor associated antigens and the concept of tumor markers.
Describe local and systemic adverse effects of tumors on the host with special emphasis on paraneoplastic syndromes.
Discuss the changes in cancer incidence that occurred over the last 100 years and list the 3 most common forms of cancer in men and women previously and now.
Describe the geographic differences in the incidence of the main forms of cancer.
Define the listed Keywords.
Be able to identify, from projected slides, each of the diseases/processes listed in the Supplemental Image Database.