At the completion of this unit, the student will be able to ...

1. Describe the differences between subsets of lymphocytes, specifically CD3, CD4, and CD8.

2. Describe the antigen-presenting cells and discuss their function, particularly with regard to the role of the major histocompatibility complex.

3. Describe the pathogenesis of a type I hypersensitivity reaction and list 2 examples.

4. Describe the pathogenesis of a type II hypersensitivity reaction and list 2 examples.

5. Describe the pathogenesis of a type III hypersensitivity reaction and list 2 examples.

6. Describe the pathogenesis of a type IV hypersensitivity reaction and list 2 examples.

7. Discuss the complications of solid organ transplantation and bone marrow transplantation.

8. List 3 congenital immunodeficiency diseases and 3 acquired immunodeficiency diseases and explain their pathogenesis.

9. Define the listed keywords.

10. Identify key features and be able to recognize from projected slides each of the diseases/processes depicted in the Supplemental Image Database.