At the completion of this unit, the student will be able to ...

1. List the 3 most common sexually transmitted diseases causing genital ulcers, and describe the typical pathology.

2. Discuss the pathogenesis, bacteriology, clinical symptoms and complications of pelvic inflammatory disease.

3. Describe the natural history, pathology and evolution of vulvar and vaginal carcinomas and vulvar and vaginal intraepithelial neoplasia.

4. Discuss the pathogenesis and the pathology of DES induced vaginal lesions.

5. Discuss uterine cervical carcinoma, listing risk factors, pathogenic factors (especially viruses) and pathology.

6. Define endometriosis and adenomyosis, discuss the main theories explaining the pathogenesis of endometriosis and list the most common sites of endometriosis and relate these to typical clinical symptoms.

7. Contrast and compare the various forms of endometrial hyperplasia and adenocarcinoma, list the risk factors.

8. Describe the gross and microscopic features of uterine leiomyoma and relate these to clinical symptoms.

9. Describe the pathology and complications of ectopic pregnancy.

10. Describe three most common solitary ovarian cysts and compare them with the polycystic ovary syndrome.

11. List the most important cell types of the ovary that could give rise to tumors, and list three tumors derived from each cell type.

12. List the 5 most important germ cell tumors of the ovary and describe their pathologic features.

13. Contrast and compare thecoma, fibroma, granulosa cell, and Sertoli- Leydig tumor of the ovary.

14. Discuss the complication of infections during pregnancy.

15. Discuss the pathogenesis and pathology of toxemia of pregnancy and relate the pathologic findings to clinical symptoms.

16. Compare the pathology and karyotypic features of complete and partial hydatidiform mole.

17. Describe the pathology of choriocarcinoma and relate it to clinical symptoms.

18. List the main pathologic features of fibrocystic change of breast.

19. Describe the pathology and clinical presentation of fibroadenoma.

20. List and compare the various types of intraductal and invasive carcinoma of the breast.

21. Discuss the pathogenesis of breast cancer and prognostic factors of breast cancer.

22. Define the listed Keywords.

23. Be able to identify, from projected slides, each of the diseases/processes in the Supplemental Image Database.