At the completion of this unit, the student will be able to ...

1. Describe the most important motor disorders of the esophagus and list the possible causes of these disturbances.

2. Describe the pathology of congenital atresia of the esophagus and associated tracheal lesions.

3. Discuss the gross appearance, histopathology, clinical course, and the route of metastasis of esophageal carcinoma.

4. List 3 environmental conditions that may play a role in pathogenesis of esophageal carcinoma.

5. Describe esophageal varices, their pathogenesis and typical complications.

6. Discuss the pathogenesis of acute (erosive) gastritis.

7. Discuss the pathogenesis and the morphology of stress ulcers.

8. Contrast and compare duodenal and gastric peptic ulcers, and their typical complications.

9. Describe typical gross and histologic features of gastric carcinoma.

10. Discuss the epidemiology and risk factors of gastric carcinoma.

11. Correlate the pathologic findings and clinical symptoms of gastric carcinoma.

12. Describe the typical features of gastrointestinal lymphoma.

13. Contrast and compare the pathology of ulcerative colitis and Crohn disease, and list typical complications of each of these diseases.

14. List the most important viral, bacterial and parasitic pathogens causing enterocolitis.

15. Contrast and compare diarrheal disease caused by enterotoxin-producing bacteria (staph) and diarrhea due to enteroinvasive microbes (Shigella).

16. Describe the pathologic lesions in pseudomembranous colitis, and discuss the etiology and pathogenesis of this disease.

17. List four benign colonic tumors and describe their pathology.

18. Discuss the clinical significance of colonic polyps and their relationship to cancer.

19. Describe the epidemiology and pathology of colorectal carcinoma.

20. Contrast and compare the pathology and the clinical presentation of carcinoma of the right vs. left colon.

21. List 4 mechanical causes of intestinal obstruction.

22. Describe the pathogenesis and pathology of appendicitis, and list the most common complications.

23. Define the listed Keywords.

24. Be able to identify, from projected slides, each of the diseases/processes in the Supplemental Image Database.