UNSW Embryology

Early Human Carnegie Stages

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Stage Sequence

Embryo Growth Movie

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Stage
Days (approx)
Size (mm)
Images
(not to scale, click image to see original)

Somite Number

Events

1
1

(week 1)

0.1-0.15

fertilized oocyte

2
2 - 3

0.1-0.2

inner and outer cell mass

3
4 - 5

0.1-0.2

free blastocyst

4
5 - 6

0.1-0.2

attaching blastocyst

5
7 - 12
(week 2)
0.1-0.2

implantation

6
13 - 15
0.2

extraembryonic mesoderm, primitive streak

7
15 - 17

(week 3)

0.4

gastrulation, notochordal process

8
17 - 19
1.0 - 1.5

primitive pit, notochordal canal

9
19 - 21
1.5 - 2.5

1 - 3

neural folds, cardiac primordium, head fold

10
22 - 23

(week 4)

2 - 3.5

4 - 12

neural fold fuses

11
23 - 26
2.5 - 4.5

13 - 20

rostral neuropore closes

12
26 - 30
3 - 5

21 - 29

caudal neuropore closes

13
28 - 32

(week 4)

4 - 6

30

leg buds, lens placode

14
31 - 35
5 - 7

lens pit, optic cup

15
35 - 38
7 - 9

lens vesicle, nasal pit, hand plate

16
37 - 42

(week 6)

8 - 11

nasal pits moved ventrally, auricular hillocks, foot plate

17
42 - 44
11 - 14

finger rays

18
44 - 48

(week 7)

13 - 17

ossification commences

19
48 - 51
16 - 18

straightening of trunk

20
51 - 53

(week 8)

18 - 22

upper limbs longer and bent at elbow

21
53 - 54
22 - 24

hands and feet turned inward

22
54 - 56
23 - 28

eyelids, external ears

23
56 - 60
27 - 31

rounded head, body and limbs

Approximate stage of human serial series in Embryology Program

[Source: Rothenburger and Gay, 1995. and others]